epitalon peptide (20mg)
$60.45
Epitalon peptide (a.k.a. epi. thalon and epithalone) is a therapeutic tetrapeptide consisting of the amino acids alanine, glutamic acid, aspartic acid, and glycineAs a natural peptide, it’s isolated from epithalamin, a polypeptide produced in bovine pineal glands.
Epitalon peptide (a.k.a. epi. thalon and epithalone) is a therapeutic tetrapeptide consisting of the amino acids alanine, glutamic acid, aspartic acid, and glycineAs a natural peptide, it’s isolated from epithalamin, a polypeptide produced in bovine pineal glands. It can also be lab-synthesized.
The Epitalon peptide has gained interest in longevity research as a potential bioregulator that may influence cellular aging processes. Most notably, Epithalon has been studied for its potential as a modulator of telomerase, an enzyme that helps maintain telomere length.
Peptide Information
| Property | Value |
|---|---|
| Peptide Sequence | Ala-Glu-Asp-Gly |
| Molecular Formula | C14H22N4O9 |
| Molecular Weight | 390.35 g/mol |
| CAS Number | 307297-39-8 |
| PubChem CID | 219042 |
| Synonyms | 307297-39-8, Glycine, L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-, Ala-Glu-Asp-Gly |
Epitalon Peptide Benefits
Core Therapeutic Applications of Epitalon
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Anti-Aging & Cellular Lifespan: Lengthens telomeres, delays cellular senescence, reduces age-related chromosome aberrations, and provides antioxidant protection against oxidative stress.
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Sleep Optimization: Boosts melatonin synthesis (by up to 160% in human trials), helping regulate circadian rhythms and improve overall sleep quality.
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Immunity & Tumor Suppression: Enhances immune system regulation and reduces tumor frequency/size by preserving telomere length and increasing immunocompetent cell activity.
Secondary Cascading Benefits
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Cardiovascular Health: Supports heart function by mitigating telomere dysfunction (a factor in hypertension and heart failure) and improving sleep.
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Hormonal Balance: Directly supports hormone levels and boosts melatonin, which helps alleviate symptoms of processes like menopause.
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Skin Vitality: Slows visible aging (e.g., wrinkles) by protecting high-turnover skin cells from accelerated telomere shortening.
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Cognitive & Mental Wellness: Better sleep and hormonal balance downstream promote improved energy, mood, stress resilience, and executive function.
Safety Overview of epitalon peptide
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Clinical Profile: Epitalon peptide appears broadly safe based on limited long-term human trials (including a notable 2002 study with 162 patients) showing no severe side effects. However, a 2025 review emphasizes that critical safety data remains incomplete.
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FDA Warnings: The FDA flags epitalon for potential immunogenicity—where the body triggers a potentially life-threatening immune reaction.
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Precautions: It is contraindicated for pregnant or breastfeeding women, and individuals with active or suspected cancer should consult a doctor first.
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Supply Risks: Epitalon is largely sold online as research-grade rather than pharmaceutical-grade, posing high risks of low purity, contamination, and adverse reactions.
Administration & Dosing
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Dose & Method: Typically 1 mg injected subcutaneously (belly, arm, thigh) 5 days/week, ideally at night (supports melatonin).
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Preparation: Powder reconstituted with bacteriostatic water using provided supplies (syringes, alcohol swabs).
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Cycling: Usually 1 month on, 3 months off (3 cycles per year).
Timeline of Benefits
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Weeks 1–2: Improved sleep quality, boosting energy, mood, cognition, and stress resilience.
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Weeks 4–6: Better skin health and reduced oxidative stress.
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Weeks 8–12+: Long-term longevity benefits, including stronger immunity, cellular health, and improved cardiovascular and cognitive function.
Storage
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Keep reconstituted peptides refrigerated at 4°C (39°F) to preserve stability.
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